Clutter can make life much more difficult than it needs to be. Taking one room at a time, go through it and gather anything that hasn't been used more than once in the last year, as well as anything that has no real value to you, or relevance. If it has true value for you, keep it. If it has no value at all, discard it. If it has value, but not especially to you, donate it to charity and take a tax deduction. Make sure to get a receipt from the charity organization you donate to and if you're donating high value items consult with your accountant to find an charity approved for tax deduction.
Disclaimer: I am not a lawyer, accountant, or tax professional and the content with my posts are for entertainment purposes only.